Opioid MEQ Equation:
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The Opioid MEQ (Morphine Equivalent) equation calculates the morphine equivalent dose for opioid medications based on the specific drug's potency factor. This helps standardize opioid dosing and monitor for potential overdose risk.
The calculator uses the MEQ equation:
Where:
Explanation: The equation converts various opioid doses to their morphine equivalent to standardize potency comparisons and monitor total opioid exposure.
Details: MEQ calculation is essential for safe opioid prescribing, monitoring for potential overdose risk, converting between different opioid medications, and ensuring appropriate pain management while minimizing addiction potential.
Tips: Enter the opioid dose in milligrams and the specific adult conversion factor for the medication. All values must be valid positive numbers.
Q1: What is a typical adult factor for common opioids?
A: Conversion factors vary by medication. For example: morphine = 1, oxycodone = 1.5, hydromorphone = 4-5, fentanyl has variable conversion based on route.
Q2: Why is MEQ calculation important?
A: It helps standardize opioid dosing across different medications, monitor for potential overdose risk, and ensure safe prescribing practices.
Q3: Are there limitations to MEQ calculations?
A: Yes, individual patient factors, tolerance, renal/hepatic function, and genetic differences can affect opioid metabolism and response.
Q4: When should MEQ calculations be used?
A: For all opioid prescribing, when converting between opioids, when monitoring total opioid exposure, and when assessing overdose risk.
Q5: What are safe MEQ dosage ranges?
A: Guidelines vary, but generally 50-90 MEQ/day is considered moderate risk, while >90 MEQ/day is considered higher risk requiring careful monitoring.